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COMPANY

Memgen

HQ: Houston, TX source · memgenbio.com ↗ · Southwest

Clinical Phase 1

Memgen is applying its expertise in immune-regulatory systems to develop a range of immunotherapies, including viral immunotherapies, cell-based immunotherapies (TILs), and infectious disease vaccine adjuvants. From company website Source · Oct 13, 2026

Keywords: Chronic Lymphocytic Leukemia Non Small Cell Lung Cancer Cutaneous Squamous Cell Carcinoma Merkel Cell Carcinoma Melanoma Pancreatic Cancer Triple Negative Breast Cancer Head and Neck Cancer ISF35

Location: Houston, TX · source · Oct 14, 2026

Profile checked Oct 10, 2026

4Trials (company is sponsor)

Timeline

  1. Trial start Phase 1: MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors source ↗
  2. Trial start I: A Phase Ib Study of ISF35 in Combination With Chemotherapy (FCR) in Subjects With Relapsed, Refractory, and/or 17p- CLL source ↗
  3. Trial start I: A Phase I Extension Trial of Repeated Infusions of ISF35 source ↗
  4. Trial start I: A Phase I Trial of Autologous CLL B Cells Transduced to Express Chimeric CD154 (ISF35) source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 4

RecordTitlePhaseStatusStartPrimary completion
NCT05076760MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid TumorsPhase 1RecruitingApr 21, 20222027-02 (estimated)
NCT00772486A Phase Ib Study of ISF35 in Combination With Chemotherapy (FCR) in Subjects With Relapsed, Refractory, and/or 17p- CLLICompleted2008-092011-04 (actual)
NCT00783588A Phase I Extension Trial of Repeated Infusions of ISF35ICompleted2007-052008-09 (actual)
NCT00779883A Phase I Trial of Autologous CLL B Cells Transduced to Express Chimeric CD154 (ISF35)ICompleted2006-062008-03 (actual)
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