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COMPANY

Mediar Therapeutics

HQ: Boston, MA source · mediartx.com ↗

Clinical Phase 2

He joined Mediar from Pfizer, where he spent more than 20 years focused on drug discovery and development. From company website Source · Oct 12, 2026

Keywords: drug discovery Diffuse Cutaneous Systemic Sclerosis Idiopathic Pulmonary Fibrosis Diabetic Kidney Disease MTX-463 MTX-474 MTX-439

Location: Boston, MA · source · Oct 14, 2026

Profile checked Oct 10, 2026

6Trials (company is sponsor)

Funding and NIH signals

Job counts as of Oct 18, 2026. All funding and NIH signals

Raises and deals from press releases

From the company’s own releases; this list is partial. All raises and deals

Timeline

  1. Trial start Phase 1: Evaluation of MTX-439 in Healthy Adults and Adults With Diabetic Kidney Disease source ↗
  2. Trial start Phase 2: EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc) source ↗
  3. Trial start Phase 1: Evaluation of MTX-463 Administered Subcutaneously in Healthy Adult Males source ↗
  4. Trial start Phase 2: WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF) source ↗
  5. Trial start Phase 1: A First-in-Human Safety Trial of MTX-474 source ↗
  6. Trial start Phase 1: A First-in-Human Safety Trial of MTX-463 source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 6

RecordTitlePhaseStatusStartPrimary completion
NCT07287670EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)Phase 2RecruitingApr 16, 20262028-12 (estimated)
NCT06967805WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)Phase 2RecruitingMay 5, 20252027-08 (estimated)
NCT07473323Evaluation of MTX-439 in Healthy Adults and Adults With Diabetic Kidney DiseasePhase 1RecruitingMay 19, 20262027-05 (estimated)
NCT07450521Evaluation of MTX-463 Administered Subcutaneously in Healthy Adult MalesPhase 1CompletedFeb 18, 2026Mar 11, 2026 (actual)
NCT06535841A First-in-Human Safety Trial of MTX-474Phase 1CompletedJul 10, 2024Apr 24, 2025 (actual)
NCT06401213A First-in-Human Safety Trial of MTX-463Phase 1CompletedApr 15, 2024Nov 15, 2024 (actual)

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