COMPANY

BioJiva

Location: San Jose, CA · source · Oct 15, 2026

Profile checked Oct 10, 2026

Keywords: Infantile Neuroaxonal Dystrophy Friedreich's Ataxia Geographic Atrophy Amyotrophic Lateral Sclerosis Progressive Supranuclear Palsy RT001 BRX011

8Trials (company is sponsor)

Timeline

Sep 29, 2026 Trial start 1: A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration source ↗
Jun 23, 2021 Trial start Phase 2: RT001 in Patients With Progressive Supranuclear Palsy (PSP) PROGRESSIVE SUPRANUCLEAR PALSY source ↗
Mar 10, 2021 Trial start Phase 2: RT001 in Amyotrophic Lateral Sclerosis source ↗
Oct 30, 2019 Trial start Phase 3: A Study to Assess Efficacy, Long Term Safety and Tolerability of RT001 in Subjects With Friedreich's Ataxia source ↗
Jun 17, 2019 Trial start —: A Natural History Study of Infantile Neuroaxonal Dystrophy source ↗
Nov 5, 2018 Trial start Phase 2/Phase 3: A Study to Assess Efficacy and Safety of RT001 in Subjects With Infantile Neuroaxonal Dystrophy source ↗
Jul 30, 2018 Trial start —: Natural History of Infantile Neuroaxonal Dystrophy source ↗
2015-08 Trial start Phase 1/Phase 2: A First in Human Study of RT001 in Patients With Friedreich's Ataxia source ↗

Upcoming milestones

2029-04 (ESTIMATED) · 1 · A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration · NCT07029945

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 8

Record	Title	Phase	Status	Start	Primary completion
NCT07029945	A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration	1	Recruiting	Sep 29, 2026	2029-04 (estimated)
NCT04762589	RT001 in Amyotrophic Lateral Sclerosis	Phase 2	Completed	Mar 10, 2021	Jun 28, 2022 (actual)
NCT04102501	A Study to Assess Efficacy, Long Term Safety and Tolerability of RT001 in Subjects With Friedreich's Ataxia	Phase 3	Completed	Oct 30, 2019	Aug 23, 2021 (actual)
NCT04027816	A Natural History Study of Infantile Neuroaxonal Dystrophy	Not listed	Completed	Jun 17, 2019	Feb 14, 2022 (actual)
NCT03570931	A Study to Assess Efficacy and Safety of RT001 in Subjects With Infantile Neuroaxonal Dystrophy	Phase 2/Phase 3	Active, not recruiting	Nov 5, 2018	Aug 9, 2020 (actual)
NCT04937530	RT001 in Patients With Progressive Supranuclear Palsy (PSP) PROGRESSIVE SUPRANUCLEAR PALSY	Phase 2	Unknown status (ClinicalTrials.gov)	Jun 23, 2021	Jul 30, 2022 (estimated)
NCT02445794	A First in Human Study of RT001 in Patients With Friedreich's Ataxia	Phase 1/Phase 2	Completed	2015-08	2016-06 (actual)
NCT03999814	Natural History of Infantile Neuroaxonal Dystrophy	Not listed	Completed	Jul 30, 2018	Feb 27, 2020 (actual)