Biotech RadarJobs updated

COMPANY

Orbus Therapeutics

HQ: Menlo Park, CA source · orbustherapeutics.com ↗

Clinical Phase 1

Keywords: rare disease IDH-wildtype Glioblastoma Glioblastoma Glioblastoma Multiforme Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype GBM Astrocytoma IDH-Mutant Astrocytoma Anaplastic Astrocytoma Recurrent Anaplastic Astrocytoma

Location: Menlo Park, CA · source · Oct 12, 2026

Profile checked Oct 10, 2026

2Trials (company is sponsor)

Timeline

  1. Trial start Phase 1: Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma source ↗
  2. Trial start Phase 3: Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients source ↗

Clinical trials (lead sponsor) 2

RecordTitlePhaseStatusStartPrimary completion
NCT05879367Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or AstrocytomaPhase 1RecruitingJul 24, 2023Jun 30, 2026 (estimated)
NCT02796261Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) PatientsPhase 3Unknown status (ClinicalTrials.gov)2016-072023-06 (estimated)
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