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COMPANY

DermBiont

HQ: Boston, MA source · dermbiont.com ↗

Clinical Phase 2

Keywords: dermatology small molecule microbiome Tinea Pedis Seborrheic Keratosis Atopic Dermatitis Tinea Versicolor Melasma Non-Melanoma Skin Cancers Dermatosis Papulosa Nigra Hyperpigmentation Onychomycosis Interdigital Tinea Pedis SM-020 DBI-001 Janthinobacterium lividum SM-030 DBI-102 DBI-002 J. lividum

Location: Boston, MA · source · Oct 12, 2026

Profile checked Oct 10, 2026

13Trials (company is sponsor)

Timeline

  1. Trial start Phase 2: Randomized Study Using SM-030 Gel for Adults With Melasma source ↗
  2. Trial start Phase 2: A Trial to Study the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratoses and Non-Melanoma Skin Cancers source ↗
  3. Trial start Phase 2: A Trial to Study the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Dermatosis Papulosa Nigra (DPN) source ↗
  4. Trial start Phase 2: A Trial to Evaluate the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratosis source ↗
  5. Trial start Phase 2: A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Onychomycosis source ↗
  6. Trial start Phase 2: A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Tinea Pedis source ↗
  7. Trial start Phase 2: Randomized and Open Label Study for Safety and Efficacy of DBI-102 vs. Vehicle vs. Hydroquinone on Skin Pigmentation and Lentigos source ↗
  8. Trial start Phase 2: Adaptive Design Study for Safety and Efficacy of Treatment Regimens With SM-020 in Subjects With Seborrheic Keratosis source ↗
  9. Trial start Phase 2: Study the Safety and Efficacy of DBI-001 Gel Versus Aqueous Gel source ↗
  10. Trial start Phase 2: A Trial to Evaluate the Safety and Antimicrobial Efficacy of DBI-002 Probiotic in Adults With Tinea Versicolor source ↗
  11. Trial start Phase 2: A Trial of Safety/Efficacy of Test Article in Patients With Interdigital T. Pedis source ↗
  12. Trial start Phase 2: Observer-Blinded Dose Escalating, Single Dose to Study Safety and Antimicrobial Efficacy of Gel vs. Placebo source ↗
  13. Trial start Phase 2: A Trial to Evaluate the Safety and and Tolerability of DBI-001 in Patients With Tinea Pedis source ↗

Clinical trials (lead sponsor) 13

RecordTitlePhaseStatusStartPrimary completion
NCT04937920A Trial to Evaluate the Safety and Antimicrobial Efficacy of DBI-002 Probiotic in Adults With Tinea VersicolorPhase 2CompletedMar 16, 2021Sep 20, 2021 (actual)
NCT04152226A Trial to Evaluate the Safety and and Tolerability of DBI-001 in Patients With Tinea PedisPhase 2CompletedFeb 19, 2019Apr 30, 2019 (actual)
NCT06454747Randomized Study Using SM-030 Gel for Adults With MelasmaPhase 2RecruitingJun 27, 20242025-04 (estimated)
NCT06108024A Trial to Evaluate the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic KeratosisPhase 2Unknown status (ClinicalTrials.gov)Nov 6, 2023Sep 15, 2024 (estimated)
NCT06409195A Trial to Study the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratoses and Non-Melanoma Skin CancersPhase 2Unknown status (ClinicalTrials.gov)Mar 25, 20242024-11 (estimated)
NCT06099080A Trial to Study the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Dermatosis Papulosa Nigra (DPN)Phase 2Unknown status (ClinicalTrials.gov)Nov 7, 2023Jul 25, 2024 (estimated)
NCT05253755Study the Safety and Efficacy of DBI-001 Gel Versus Aqueous GelPhase 2TerminatedOct 6, 2021Sep 9, 2022 (actual)
NCT05511948Randomized and Open Label Study for Safety and Efficacy of DBI-102 vs. Vehicle vs. Hydroquinone on Skin Pigmentation and LentigosPhase 2CompletedAug 18, 2022Mar 7, 2023 (actual)
NCT05136144Adaptive Design Study for Safety and Efficacy of Treatment Regimens With SM-020 in Subjects With Seborrheic KeratosisPhase 2Unknown status (ClinicalTrials.gov)Oct 19, 2021May 31, 2024 (estimated)
NCT05491603A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With OnychomycosisPhase 2Suspended2023-11Nov 30, 2023 (estimated)
NCT05493488A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Tinea PedisPhase 2Unknown status (ClinicalTrials.gov)Sep 8, 2022Dec 31, 2023 (estimated)
NCT04192513Observer-Blinded Dose Escalating, Single Dose to Study Safety and Antimicrobial Efficacy of Gel vs. PlaceboPhase 2TerminatedMay 20, 2019Jun 30, 2020 (actual)
NCT04315051A Trial of Safety/Efficacy of Test Article in Patients With Interdigital T. PedisPhase 2TerminatedSep 12, 2019Jun 30, 2020 (actual)
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