COMPANY
Clinical Phase 2
Keywords: oncology cancer synthetic lethality High Grade Serous Adenocarcinoma of Ovary Chromosomal Instability Squamous Non-small-cell Lung Cancer Triple Negative Breast Cancer Head and Neck Squamous Cell Carcinoma Ovarian Carcinosarcoma Uterine Carcinosarcoma Uterine Serous Carcinoma Endometrium Cancer Fallopian Tube Cancer Primary Peritoneal Carcinoma VLS-1488 Sovilnesib AMG 650
Location: New York, NY · source · Oct 14, 2026
Profile checked Oct 10, 2026
Timeline
- Trial start Phase 1: A Study of Sovilnesib in Subjects With Ovarian Cancer source ↗
- Trial start I: A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer source ↗
- Trial start Phase 1: Study of AMG 650 in Adult Participants With Advanced Solid Tumors source ↗
Clinical trials (lead sponsor) 3
| Record | Title | Phase | Status | Start | Primary completion |
|---|
| NCT05902988 | A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer | I | Recruiting | Oct 18, 2023 | 2026-06 (estimated) |
| NCT06084416 | A Study of Sovilnesib in Subjects With Ovarian Cancer | Phase 1 | Active, not recruiting | Apr 4, 2024 | 2026-03 (estimated) |
| NCT04293094 | Study of AMG 650 in Adult Participants With Advanced Solid Tumors | Phase 1 | Completed | Mar 11, 2020 | Oct 24, 2022 (actual) |
