COMPANY
Replimune
FDA-approved therapeutic company Clinical Phase 3
Since the raise (Nov 26, 2024): 44 of 44 open jobs were first seen after it.
Hiring
| Title | Location (from posting) | Employer posted | First seen |
|---|---|---|---|
| Manager, FP&A | Woburn, Massachusetts, United States | Oct 19, 2026 | Oct 20, 2026 |
| Analyst I, Analytical Services | Framingham, Massachusetts, United States | Oct 15, 2026 | Oct 16, 2026 |
| Associate Director, Analytical Services | Framingham, Massachusetts, United States | Oct 15, 2026 | Oct 16, 2026 |
| Sr. Medical Science Liaison II - New England | Woburn, Massachusetts, United States | Oct 15, 2026 | Oct 16, 2026 |
| Quality Control Laboratory Technician | Abingdon, Oxfordshire, United Kingdom | Oct 14, 2026 | Oct 8, 2026 |
Trial and FDA signals
- FDA complete response letter Received an FDA complete response letter (BL 125827, letter dated Apr 10, 2026); 46 roles open. FDA BL 125827 (Apr 10, 2026)
Evidence (1 event)
- Apr 10, 2026 · FDA BL 125827
CRL text (OCR, redacted by FDA; first 200 chars from "COMPLETE RESPONSE"): COMPLETE RESPONSE APRIL 10, 2026 Replimune, Inc. Attention: Kari Jeschke Woburn, MA (street omitted) Dear Kari Jeschke: Please refer to your Biologics License Application (BLA) received (1
- Apr 10, 2026 · FDA BL 125827
Timeline
- Board tracked Radar started tracking this company’s job board (44 open jobs at last check). source ↗
- FDA FDA New drug/biologic (novel): TUDRIQEV (vusolimogene oderparepvec-wtpg) — BLA125827, Aug 6, 2026. Applicant at approval: Replimune, Inc. source ↗
- Trial start —: A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3 source ↗
- Trial start 2: A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma source ↗
- Raise Follow-on offering: $140M (total, as published), announced Nov 26, 2024. Source: company release on GlobeNewswire. source ↗
- Trial start Phase 2: Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC source ↗
- Trial start Phase 3: VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3] source ↗
- Trial start Phase 2: Study of RP3 in Combination With Nivolumab and Other Therapy in Patients With Locoregionally Advanced or Recurrent SCCHN source ↗
- Trial start Phase 2: RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC source ↗
- Trial start Phase 1: Study of RP3 Monotherapy and RP3 in Combination With Nivolumab in Patients With Solid Tumours source ↗
- Trial start Phase 1/Phase 2: Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies source ↗
- Trial start Phase 1: Study of RP2 Monotherapy and RP2 in Combination With Nivolumab in Patients With Solid Tumors source ↗
- Trial start Phase 2: Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancer source ↗
- Trial start Phase 2: Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE) source ↗
Upcoming milestones
- Oct 31, 2026 (ESTIMATED) · Phase 1 · Study of RP2 Monotherapy and RP2 in Combination With Nivolumab in Patients With Solid Tumors · NCT04336241
- Nov 30, 2026 (ESTIMATED) · Phase 1 · Study of RP3 Monotherapy and RP3 in Combination With Nivolumab in Patients With Solid Tumours · NCT04735978
- Dec 1, 2027 (ESTIMATED) · Phase 2 · Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC · NCT05733598
- 2028-06 (ESTIMATED) · Phase 2 · Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE) · NCT03767348
- 2029-07 (ESTIMATED) · Phase 1/Phase 2 · Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies · NCT04349436
- 2030-01 (ESTIMATED) · 2 · A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma · NCT06581406
- Sep 30, 2030 (ESTIMATED) · Phase 3 · VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3] · NCT06264180
- 2030-12 (ESTIMATED) · · A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3 · NCT06887348
Open jobs 44
| Title | Location (from posting, not HQ) | Employer posted | First seen | Level |
|---|---|---|---|---|
| Manager, FP&A | Woburn, Massachusetts, United States | Oct 19, 2026 | Oct 20, 2026 | Not stated |
| Analyst I, Analytical Services | Framingham, Massachusetts, United States | Oct 15, 2026 | Oct 16, 2026 | Not stated |
| Associate Director, Analytical Services | Framingham, Massachusetts, United States | Oct 15, 2026 | Oct 16, 2026 | Not stated |
| Sr. Medical Science Liaison II - New England | Woburn, Massachusetts, United States | Oct 15, 2026 | Oct 16, 2026 | Not stated |
| Quality Control Laboratory Technician | Abingdon, Oxfordshire, United Kingdom | Oct 14, 2026 | Oct 8, 2026 | Entry |
| Associate Director, Process Development | Abingdon, Oxfordshire, United Kingdom | Oct 7, 2026 | Oct 8, 2026 | Senior |
| Senior Engineer, Technical Operations | Framingham, Massachusetts, United States | Oct 7, 2026 | Oct 8, 2026 | Senior |
| Senior Associate, Clinical Supply Chain | Framingham, Massachusetts, United States | Oct 7, 2026 | Oct 8, 2026 | Mid |
| Director, Data Analytics and Reporting | Woburn, Massachusetts, United States | Oct 7, 2026 | Oct 8, 2026 | Senior |
| Validation Engineer II | Framingham, Massachusetts, United States | Oct 6, 2026 | Oct 8, 2026 | Mid |
| Associate Director, Facilities and Engineering | Abingdon, Oxfordshire, United Kingdom | Oct 2, 2026 | Oct 8, 2026 | Senior |
| Senior Quality Control Analyst | Abingdon, Oxfordshire, United Kingdom | Oct 1, 2026 | Oct 8, 2026 | Senior |
| Quality Control Analyst I | Abingdon, Oxfordshire, United Kingdom | Oct 1, 2026 | Oct 8, 2026 | Entry |
| QC Microbiology Technician | Framingham, Massachusetts, United States | Oct 1, 2026 | Oct 8, 2026 | Mid |
| Senior Quality Control, Microbiology Analyst | Framingham, Massachusetts, United States | Oct 1, 2026 | Oct 8, 2026 | Senior |
| Director, Medical Publications and Scientific Communication | Woburn, Massachusetts, United States | Sep 30, 2026 | Oct 8, 2026 | Senior |
| Director, Clinical Scientist | Woburn, Massachusetts, United States | Sep 29, 2026 | Oct 8, 2026 | Senior |
| Associate I, PDT | Framingham, Massachusetts, United States | Sep 29, 2026 | Oct 8, 2026 | Entry |
| Senior Associate, Quality Systems | Framingham, Massachusetts, United States | Sep 28, 2026 | Oct 8, 2026 | Mid |
| Director, IT Business Partner Commercial | Woburn, Massachusetts, United States | Sep 25, 2026 | Oct 8, 2026 | Senior |
| Sr. Medical Science Liaison II (New York/New Jersey) | Woburn, Massachusetts, United States | Sep 25, 2026 | Oct 8, 2026 | Senior |
| Sr. Manager, Regulatory Operations (Publishing) | Woburn, Massachusetts, United States | Sep 24, 2026 | Oct 8, 2026 | Senior |
| Senior Scientist, Drug Product | Framingham, Massachusetts, United States | Sep 24, 2026 | Oct 8, 2026 | Senior |
| Pharmacovigilance Scientist | Woburn, Massachusetts, United States | Sep 23, 2026 | Oct 8, 2026 | Mid |
| Analyst II, Analytical Development | Abingdon, Oxfordshire, United Kingdom | Sep 21, 2026 | Oct 8, 2026 | Mid |
| Analyst II, Analytical Development | Abingdon, Oxfordshire, United Kingdom | Sep 21, 2026 | Oct 8, 2026 | Mid |
| Scientist I, Analytical Development | Abingdon, Oxfordshire, United Kingdom | Sep 21, 2026 | Oct 8, 2026 | Entry |
| Scientist I, Quality Control | Abingdon, Oxfordshire, United Kingdom | Sep 18, 2026 | Oct 8, 2026 | Entry |
| Scientist I, Quality Control | Abingdon, Oxfordshire, United Kingdom | Sep 18, 2026 | Oct 8, 2026 | Entry |
| Quality Assurance Officer I | Abingdon, Oxfordshire, United Kingdom | Sep 17, 2026 | Oct 8, 2026 | Entry |
| Senior Manager, Clinical Scientist | Woburn, Massachusetts, United States | Sep 16, 2026 | Oct 8, 2026 | Senior |
| Director, Qualified Person | Abingdon, Oxfordshire, United Kingdom | Sep 14, 2026 | Oct 8, 2026 | Senior |
| Director, Information Technology | Woburn, Massachusetts, United States | Sep 11, 2026 | Oct 8, 2026 | Senior |
| Regional Director - MSL East | Woburn, Massachusetts, United States | Sep 10, 2026 | Oct 8, 2026 | Senior |
| Director, HR Business Partner | Abingdon, Oxfordshire, United Kingdom | Sep 8, 2026 | Oct 8, 2026 | Senior |
| Executive Director, Market Access and Value | Woburn, Massachusetts, United States | Sep 8, 2026 | Oct 8, 2026 | Executive |
| Senior Manager, Data Management | Woburn, Massachusetts, United States | Sep 3, 2026 | Oct 8, 2026 | Senior |
| Operational Excellence Lead I (PharmD) | Woburn, Massachusetts, United States | Aug 28, 2026 | Oct 8, 2026 | Senior |
| Sr. Scientist, Process Development & Technology | Framingham, Massachusetts, United States | Aug 26, 2026 | Oct 8, 2026 | Senior |
| Sr. Director, Clinical Scientist | Woburn, Massachusetts, United States | Aug 26, 2026 | Oct 8, 2026 | Senior |
| Sr. Director, Patient Support Services | Woburn, Massachusetts, United States | Aug 19, 2026 | Oct 8, 2026 | Senior |
| Senior Director, Trade & Distribution | Woburn, Massachusetts, United States | Aug 19, 2026 | Oct 8, 2026 | Senior |
| Medical Director, Global Drug Safety | Woburn, Massachusetts, United States | Aug 6, 2026 | Oct 8, 2026 | Senior |
| Process and Equipment Engineer II | Framingham, Massachusetts, United States | Jul 20, 2026 | Oct 8, 2026 | Mid |
Funding
- Follow-on offering: $140M (total, as published), announced Nov 26, 2024. Source: company release on GlobeNewswire. source ↗
Clinical trials (lead sponsor) 12
| Record | Title | Phase | Status | Start | Primary completion |
|---|---|---|---|---|---|
| NCT06264180 | VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3] | Phase 3 | Recruiting | Jul 11, 2024 | Sep 30, 2030 (estimated) |
| NCT04349436 | Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies | Phase 1/Phase 2 | Active, not recruiting | May 15, 2020 | 2029-07 (estimated) |
| NCT06581406 | A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma | 2 | Recruiting | Dec 17, 2024 | 2030-01 (estimated) |
| NCT05733598 | Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC | Phase 2 | Recruiting | Aug 1, 2024 | Dec 1, 2027 (estimated) |
| NCT04336241 | Study of RP2 Monotherapy and RP2 in Combination With Nivolumab in Patients With Solid Tumors | Phase 1 | Active, not recruiting | Oct 17, 2019 | Oct 31, 2026 (estimated) |
| NCT04735978 | Study of RP3 Monotherapy and RP3 in Combination With Nivolumab in Patients With Solid Tumours | Phase 1 | Active, not recruiting | Dec 29, 2020 | Nov 30, 2026 (estimated) |
| NCT03767348 | Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE) | Phase 2 | Active, not recruiting | Sep 20, 2017 | 2028-06 (estimated) |
| NCT05733611 | RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC | Phase 2 | Terminated | Jun 29, 2023 | Aug 18, 2025 (actual) |
| NCT06887348 | A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3 | Not listed | Recruiting | Dec 12, 2025 | 2030-12 (estimated) |
| NCT06590480 | An Expanded Access Program for VO (RP1) in Combination With Nivolumab in Patients With Advanced Melanoma | Not listed | No longer available | Not listed | Not listed |
| NCT05743270 | Study of RP3 in Combination With Nivolumab and Other Therapy in Patients With Locoregionally Advanced or Recurrent SCCHN | Phase 2 | Withdrawn | Jan 30, 2024 | Mar 1, 2026 (estimated) |
| NCT04050436 | Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancer | Phase 2 | Active, not recruiting | Oct 8, 2019 | 2025-09 (estimated) |
FDA records (last 2 years)
- FDA New drug/biologic (novel): TUDRIQEV (vusolimogene oderparepvec-wtpg) — BLA125827, Aug 6, 2026. Applicant at approval: Replimune, Inc. source ↗
Raises and investors new
- InvestorListed in the portfolio of Atlas Venture (captured Oct 12, 2026). portfolio page ↗
- InvestorListed in the portfolio of Bain Capital Life Sciences (captured Oct 12, 2026). portfolio page ↗
Connect
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