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COMPANY

Renibus Therapeutics

HQ: Southlake, TX source · renibus.com ↗

Clinical Phase 3

Keywords: renal cardiovascular Chronic Kidney Disease Post-Operative Complications in Cardiac Surgery CKD Metabolic Acidosis Post-discharge Outcomes AKI COVID-19 Acute Kidney Injury RBT-1 Veverimer RBT-9 RBT-3

Location: Southlake, TX · source · Oct 15, 2026

Profile checked Oct 10, 2026

10Trials (company is sponsor)

Timeline

  1. Trial start Phase 3: A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic Acidosis source ↗
  2. Trial start —: Retrospective Observational Study of Patients Who Have Undergone Coronary Artery Bypass Graft (CABG) and/or Cardiac Valve Surgery source ↗
  3. Trial start Phase 3: Effect of RBT-1 on Reducing the Risk of Post-Operative Complications in Subjects Undergoing Cardiac Surgery source ↗
  4. Trial start —: An Evaluation of Patient Reported Outcomes and Clinical Outcomes source ↗
  5. Trial start Phase 2: Effect of RBT-1 on Preconditioning Response Biomarkers in Subjects Undergoing CABG and/or Cardiac Valve Surgery source ↗
  6. Trial start Phase 2: A Study to Evaluate the Effect of RBT-9 on Progression of COVID-19 in High-Risk Individuals (The PREVENT Study) source ↗
  7. Trial start Phase 1: A Study of RBT-1 in Healthy Volunteers and Subjects With Stage 3/4 Chronic Kidney Disease source ↗
  8. Trial start Phase 1: A Study of RBT-9 in Healthy Volunteers and Volunteers With Stage 3/4 Chronic Kidney Disease source ↗
  9. Trial start Phase 1: A Study of RBT-3 in Healthy Volunteers and Volunteers With Stage 3/4 Chronic Kidney Disease source ↗
  10. Trial start 1: RBT-1 Phase 1b Clinical Trial in Healthy Volunteers and Subjects With CKD source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 10

RecordTitlePhaseStatusStartPrimary completion
NCT07355062A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic AcidosisPhase 3RecruitingJan 13, 20262027-06 (estimated)
NCT06092970An Evaluation of Patient Reported Outcomes and Clinical OutcomesNot listedTerminatedOct 16, 2023Feb 6, 2026 (actual)
NCT03893799A Study of RBT-1 in Healthy Volunteers and Subjects With Stage 3/4 Chronic Kidney DiseasePhase 1CompletedAug 27, 2019Apr 22, 2020 (actual)
NCT06021457Effect of RBT-1 on Reducing the Risk of Post-Operative Complications in Subjects Undergoing Cardiac SurgeryPhase 3CompletedOct 17, 2023Jun 17, 2025 (actual)
NCT07009340Retrospective Observational Study of Patients Who Have Undergone Coronary Artery Bypass Graft (CABG) and/or Cardiac Valve SurgeryNot listedActive, not recruitingNov 18, 2023Jun 30, 2025 (estimated)
NCT04072861A Study of RBT-9 in Healthy Volunteers and Volunteers With Stage 3/4 Chronic Kidney DiseasePhase 1CompletedMar 31, 2019Jul 31, 2020 (actual)
NCT04072432A Study of RBT-3 in Healthy Volunteers and Volunteers With Stage 3/4 Chronic Kidney DiseasePhase 1CompletedOct 21, 2018Mar 31, 2019 (actual)
NCT04564833Effect of RBT-1 on Preconditioning Response Biomarkers in Subjects Undergoing CABG and/or Cardiac Valve SurgeryPhase 2CompletedAug 4, 2021Nov 9, 2022 (actual)
NCT04364763A Study to Evaluate the Effect of RBT-9 on Progression of COVID-19 in High-Risk Individuals (The PREVENT Study)Phase 2TerminatedAug 5, 2020Sep 2, 2021 (actual)
NCT03630029RBT-1 Phase 1b Clinical Trial in Healthy Volunteers and Subjects With CKD1WithdrawnSep 15, 2018Nov 30, 2018 (estimated)
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