COMPANY

Polares Medical

HQ: Palo Alto, CA (US office) source · polaresmedical.com ↗

Location: Palo Alto, CA (US office) · source · Oct 15, 2026

Profile checked Oct 10, 2026

Keywords: Mitral Valve Disease Mitral Valve (MV) Regurgitation Mitral Regurgitation Degenerative Mitral Valve Disease Functional Mitral Regurgitation Mitral Valve Insufficiency Transcatheter mitral valve repair (MRace Implant and Delivery System) Transcatheter mitral valve repair Transcatheter mitral valve repair (PLAR Implant and Delivery System) MR-ace Implant and Delivery System

11Trials (company is sponsor)

Timeline

2026-11 Trial start Not phased (device or behavioral study): A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (FR) source ↗
2026-11 Trial start Not phased (device or behavioral study): A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (AU) source ↗
2026-11 Trial start Not phased (device or behavioral study): A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (DE) source ↗
Sep 1, 2026 Trial start Not phased (device or behavioral study): EFS of Posterior Leaflet Replacement to Reduce Mitral Regurgitation (United States) source ↗
Mar 3, 2026 Raise Private equity round — Series C: amount not published, announced Mar 3, 2026. Source: company's own press page. source ↗
Apr 8, 2024 Trial start Not phased (device or behavioral study): EXPLORE MRace (BR): Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant source ↗
May 23, 2022 Trial start Not phased (device or behavioral study): EXPLORE MRace (GE): Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant source ↗
Apr 30, 2021 Trial start Not phased (device or behavioral study): EXPLORE DMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation source ↗
Apr 30, 2021 Trial start Not phased (device or behavioral study): EXPLORE FMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Functional Mitral Regurgitation source ↗
Apr 30, 2021 Trial start Not phased (device or behavioral study): Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation source ↗
Apr 1, 2021 Trial start Not phased (device or behavioral study): Early Feasibility Study of the PLAR Implant and Delivery System to Treat Functional Mitral Regurgitation ( EXPLORE FMR ) source ↗
Jan 1, 2020 Trial start —: Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation source ↗

Upcoming milestones

Dec 31, 2027 (ESTIMATED) · Not phased · EFS of Posterior Leaflet Replacement to Reduce Mitral Regurgitation (United States) · NCT07517588
2032-12 (ESTIMATED) · Not phased · EXPLORE MRace (BR): Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant · NCT06113354
2032-12 (ESTIMATED) · Not phased · EXPLORE MRace (GE): Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant · NCT07796659
2032-12 (ESTIMATED) · Not phased · A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (FR) · NCT07757607
2032-12 (ESTIMATED) · Not phased · A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (AU) · NCT07757698
2032-12 (ESTIMATED) · Not phased · A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (DE) · NCT07757776

Estimated primary completion per ClinicalTrials.gov. Dates move.

Funding

Raised: amount not published. Last 2 years.

Mar 3, 2026 Private equity round — Series C: amount not published, announced Mar 3, 2026. Source: company's own press page. source ↗

Clinical trials (lead sponsor) 11

Record	Title	Phase	Status	Start	Primary completion
NCT06113354	EXPLORE MRace (BR): Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant	Not phased (device or behavioral study)	Recruiting	Apr 8, 2024	2032-12 (estimated)
NCT07517588	EFS of Posterior Leaflet Replacement to Reduce Mitral Regurgitation (United States)	Not phased (device or behavioral study)	Recruiting	Sep 1, 2026	Dec 31, 2027 (estimated)
NCT07796659	EXPLORE MRace (GE): Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant	Not phased (device or behavioral study)	Recruiting	May 23, 2022	2032-12 (estimated)
NCT07757607	A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (FR)	Not phased (device or behavioral study)	Not yet recruiting	2026-11	2032-12 (estimated)
NCT07757698	A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (AU)	Not phased (device or behavioral study)	Not yet recruiting	2026-11	2032-12 (estimated)
NCT07757776	A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (DE)	Not phased (device or behavioral study)	Not yet recruiting	2026-11	2032-12 (estimated)
NCT04679662	EXPLORE DMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation	Not phased (device or behavioral study)	Withdrawn	Apr 30, 2021	2022-03 (estimated)
NCT04679714	EXPLORE FMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Functional Mitral Regurgitation	Not phased (device or behavioral study)	Withdrawn	Apr 30, 2021	2022-03 (estimated)
NCT04666480	Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation	Not phased (device or behavioral study)	Terminated	Apr 30, 2021	Dec 31, 2022 (actual)
NCT04666467	Early Feasibility Study of the PLAR Implant and Delivery System to Treat Functional Mitral Regurgitation ( EXPLORE FMR )	Not phased (device or behavioral study)	Withdrawn	Apr 1, 2021	Dec 31, 2022 (actual)
NCT04098328	Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation	Not listed	Terminated	Jan 1, 2020	Feb 2, 2023 (actual)