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COMPANY

Diasome Pharmaceuticals

HQ: Cleveland, OH source · diasome.com ↗ · Midwest

Clinical Phase 2

Keywords: metabolic diabetes mellitus obesity metabolic diseases Type 1 Diabetes Mellitus Type 2 Diabetes Mellitus Type1 Diabetes Mellitus

Location: Cleveland, OH · source · Oct 15, 2026

Profile checked Oct 10, 2026

7Trials (company is sponsor)

Raises and deals from press releases

From the company’s own releases; this list is partial. All raises and deals

Timeline

  1. Trial start 2: Phase 2b Trial Comparing HDV-Insulin Lispro to Insulin Lispro in Adults With Type 1 Diabetes Receiving Insulin Degludec source ↗
  2. Raise Series C · amount not disclosed source ↗
  3. Trial start Phase 2: Comparison of Different Insulin Dosing Algorithms Using Hepatic Directed Vesicle-Insulin Lispro and Insulin Degludec source ↗
  4. Trial start Phase 2: 21 Day Comparison of Continuous Insulin Infusion Using HDV Insulin to Standard Insulin in Type 1 Diabetes Mellitus source ↗
  5. Trial start Phase 2: Comparison of Hepatic Directed Vesicle (HDV)-Insulin Lispro Versus Insulin Lispro to Further Improve Glycemic Control source ↗
  6. Trial start —: A Single-Blind, Placebo-Controlled, Dose-Ranging Trial of Oral HDV-Insulin in Patients With Type 2 Diabetes Mellitus source ↗
  7. Trial start Phase 2: Study of HDV Insulin Versus Insulin in Type 1 Diabetes Subjects (ISLE-1) source ↗
  8. Trial start Phase 2/Phase 3: Study of Two Doses of Oral HDV-Insulin and Placebo With Background Metformin Treatment in Patients With Type 2 Diabetes Mellitus source ↗

Clinical trials (lead sponsor) 7

RecordTitlePhaseStatusStartPrimary completion
NCT06238778Phase 2b Trial Comparing HDV-Insulin Lispro to Insulin Lispro in Adults With Type 1 Diabetes Receiving Insulin Degludec2CompletedDec 28, 2023Oct 27, 2025 (actual)
NCT00814294Study of Two Doses of Oral HDV-Insulin and Placebo With Background Metformin Treatment in Patients With Type 2 Diabetes MellitusPhase 2/Phase 3Completed2008-122009-09 (actual)
NCT00521378A Single-Blind, Placebo-Controlled, Dose-Ranging Trial of Oral HDV-Insulin in Patients With Type 2 Diabetes MellitusNot listedCompletedSep 17, 2007Oct 6, 2007 (actual)
NCT03938740Comparison of Different Insulin Dosing Algorithms Using Hepatic Directed Vesicle-Insulin Lispro and Insulin DegludecPhase 2CompletedMar 18, 2019Dec 6, 2019 (actual)
NCT03096392Comparison of Hepatic Directed Vesicle (HDV)-Insulin Lispro Versus Insulin Lispro to Further Improve Glycemic ControlPhase 2CompletedApr 18, 2017Nov 15, 2017 (actual)
NCT02794155Study of HDV Insulin Versus Insulin in Type 1 Diabetes Subjects (ISLE-1)Phase 2Completed2016-06Apr 28, 2018 (actual)
NCT0315636121 Day Comparison of Continuous Insulin Infusion Using HDV Insulin to Standard Insulin in Type 1 Diabetes MellitusPhase 2CompletedMay 18, 2017Jan 15, 2018 (actual)
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