COMPANY

Revalesio

HQ: Tacoma, WA source · revalesio.com ↗ · West Coast

FDA-cleared device company Clinical Phase 2

Keywords: neurology stroke neurodegenerative disease Asthma Amyotrophic Lateral Sclerosis Ischemic Stroke Pelvic Pain Relapsing Remitting Multiple Sclerosis Systemic Bioactivity of Nebulized RNS60 Anterior Cruciate Ligament Reconstruction Hip Labral Tear Venous Stasis Ulcers Myocardial Infarct RNS60

Location: Tacoma, WA · source · Oct 14, 2026

Profile checked Oct 10, 2026

13Trials (company is sponsor)

Timeline

2026-10 Trial start Phase 2: Nebulized RNS60 for the Treatment of Amyotrophic Lateral Sclerosis source ↗
Jul 7, 2021 Trial start Phase 2: Safety of RNS60 in Large Vessel Occlusion Stroke Patients Undergoing Endovascular Thrombectomy source ↗
2015-08 Trial start Not phased (device or behavioral study): Study of Electro-kinetically Modified Water for the Treatment of Pain Associated With Endometriosis source ↗
2015-07 Trial start Phase 1: Systemic Bioactivity of Inhaled Nebulized RNS60 source ↗
2015-04 Trial start A: Effect of RNS60 on the Late Phase Asthmatic Response to Allergen Challenge source ↗
2012-06 Trial start Phase 1: Study of Inhaled RNS60 in Combination With Budesonide to Treat Mild to Moderate Asthma source ↗
2011-07 Trial start Phase 1: Safety and Tolerability of RNS60 Given by IV to Healthy Subjects source ↗
2010-05 Trial start Phase 1: Safety Study of Nebulized RNS60 to Treat Asthma. source ↗
2008-03 Trial start Phase 1: Feasibility Study to Evaluate the Safety of Topically Applied Revera in Subjects With Venous Leg Ulcers source ↗

Clinical trials (lead sponsor) 13

Record	Title	Phase	Status	Start	Primary completion
NCT02988297	Nebulized RNS60 for the Treatment of Amyotrophic Lateral Sclerosis	Phase 2	Withdrawn	2026-10	2028-11 (estimated)
NCT04693715	Safety of RNS60 in Large Vessel Occlusion Stroke Patients Undergoing Endovascular Thrombectomy	Phase 2	Completed	Jul 7, 2021	Nov 8, 2023 (actual)
NCT02523794	Study of Electro-kinetically Modified Water for the Treatment of Pain Associated With Endometriosis	Not phased (device or behavioral study)	Terminated	2015-08	2016-09 (actual)
NCT02422121	Effect of RNS60 on the Late Phase Asthmatic Response to Allergen Challenge	A	Completed	2015-04	2015-11 (actual)
NCT02497222	Pilot Study of RNS60 in Allergen-induced Bronchoconstriction	Phase 2	Withdrawn	Not listed	2016-06 (actual)
NCT01714089	Proof of Concept Study Evaluating RNS60 in the Treatment of Relapsing Remitting Multiple Sclerosis	Phase 2	Withdrawn	Not listed	Not listed
NCT02490865	Systemic Bioactivity of Inhaled Nebulized RNS60	Phase 1	Completed	2015-07	2015-08 (actual)
NCT01922427	Study of RNS60 on Pain and Function After Knee Anterior Cruciate Ligament Surgery	Phase 2	Withdrawn	Not listed	2014-10 (actual)
NCT02005523	Study of RNS60 on Pain and Function After Hip Labral Repair	Phase 2	Withdrawn	Not listed	2014-10 (actual)
NCT01511302	Study of Inhaled RNS60 in Combination With Budesonide to Treat Mild to Moderate Asthma	Phase 1	Completed	2012-06	2013-04 (actual)
NCT00823446	Feasibility Study to Evaluate the Safety of Topically Applied Revera in Subjects With Venous Leg Ulcers	Phase 1	Completed	2008-03	2010-10 (actual)
NCT01057498	Safety Study of Nebulized RNS60 to Treat Asthma.	Phase 1	Completed	2010-05	2010-11 (actual)
NCT01264783	Safety and Tolerability of RNS60 Given by IV to Healthy Subjects	Phase 1	Completed	2011-07	2011-09 (actual)