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Crinetics Pharmaceuticals, Inc.

HQ: San Diego, CA source · crinetics.com ↗ · West Coast

Status: Acquired, now part of Vertex Pharmaceuticals · How status works

FDA-approved therapeutic company Clinical Phase 3

Also known as Crinetics Pharmaceuticals · 4 open jobs · last seen Oct 23, 2026 · 37 sources

Keywords: oncology tumors Congenital Adrenal Hyperplasia Classic Congenital Adrenal Hyperplasia Acromegaly Carcinoid Syndrome Carcinoid Carcinoid Tumor Carcinoid Tumor of Ileum Carcinoid Tumor of Cecum Carcinoid Tumor of Liver Carcinoid Tumor of Pancreas Carcinoid Syndrome Diarrhea Carcinoid Intestine Tumor Cushing Syndrome Cushing Disease Ectopic ACTH Syndrome SST2-positive Neuroendocrine Neoplasms Neuroendocrine Tumors Neuroendocrine Neoplasm neuropathic pain Atumelnant Paltusotine atumelnant (CRN04894) CRN00808 CRN09682 CRN04894 CRN01941

Since the raise (Jan 6, 2026): 4 of 4 open jobs were first seen after it.

4Open jobs$350.0MRaised (2 yrs)19Trials (company is sponsor)1FDA records (2 yrs)15NIH grants

Hiring

TitleLocation (from posting)Employer postedFirst seen
Field Reimbursement Liaison - Southwest2 locations (listed on the posting)Oct 7, 2026Oct 8, 2026
Field Reimbursement Liaison - Northwest8 locations (listed on the posting)Sep 23, 2026Oct 8, 2026
Medical Director, Clinical Research, EndocrinologyRemoteSep 23, 2026Oct 8, 2026
Senior Clinical ScientistRemoteSep 23, 2026Oct 8, 2026

See all 4 jobs

Timeline

  1. Board tracked Radar started tracking this company’s job board (4 open jobs at last check). source ↗
  2. Trial start Phase 1: Drug-Drug Interaction Study of Atumelnant in Healthy Participants source ↗
  3. Trial start Phase 2/Phase 3: A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH) source ↗
  4. Raise Follow-on offering: $350M (total, as published), announced Jan 6, 2026. Source: SEC filing. source ↗
  5. Trial start Phase 3: A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia source ↗
  6. Trial start Phase 1/Phase 2: A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors source ↗
  7. Trial start Phase 3: Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen source ↗
  8. Trial start Phase 1: A Study to Assess Pharmacokinetics, Safety, and Tolerability of Atumelnant in Healthy Japanese and Caucasian Participants source ↗
  9. FDA FDA New drug/biologic (novel): PALSONIFY (paltusotine hydrochloride) — NDA219070, Sep 25, 2025. Applicant at approval: Crinetics Pharmaceuticals, Inc. source ↗
  10. Trial start Phase 2: An Extension Study to Evaluate Safety and Efficacy of Atumelnant in Participants With Congenital Adrenal Hyperplasia source ↗
  11. Trial start Phase 1/Phase 2: A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome source ↗
  12. Trial start Phase 2: Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn) source ↗
  13. Trial start Phase 2: Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid Syndrome source ↗
  14. Trial start Phase 3: A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-2) source ↗
  15. Trial start Phase 3: A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly source ↗
  16. Trial start Phase 1: Single and Multiple-Ascending Dose Study of CRN04894 in Healthy Volunteers source ↗
  17. Trial start Phase 2: A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance) source ↗
  18. Trial start Phase 1: Mass Balance and Pharmacokinetics of [14C]-CRN00808 in Healthy Volunteers source ↗
  19. Trial start Phase 1: A Single and Multiple-Ascending Dose Study of CRN01941 in Healthy Adult Volunteers source ↗
  20. Trial start Phase 2: An Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Edge) source ↗
  21. Trial start Phase 2: A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Evolve) source ↗
  22. Trial start Phase 1: Single and Multiple-Ascending Dose Study of CRN00808 in Healthy Volunteers source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Open jobs 4

TitleLocation (from posting, not HQ)Employer postedFirst seenLevel
Field Reimbursement Liaison - Southwest2 locations (listed on the posting)Oct 7, 2026Oct 8, 2026Senior
Field Reimbursement Liaison - Northwest8 locations (listed on the posting)Sep 23, 2026Oct 8, 2026Senior
Medical Director, Clinical Research, EndocrinologyRemoteSep 23, 2026Oct 8, 2026Senior
Senior Clinical ScientistRemoteSep 23, 2026Oct 8, 2026Senior

Level (Entry/Mid/Senior/Executive) is estimated from the job title and required years of experience. Descriptions are short excerpts (about the first 60 words) of the posting plus skills picked out of it; use Read full posting for the complete text.

Funding

Raised: $350.0M. Last 2 years.

Clinical trials (lead sponsor) 19

RecordTitlePhaseStatusStartPrimary completion
NCT07159841A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)Phase 2/Phase 3RecruitingJan 22, 20262030-03 (estimated)
NCT07144163A Study to Evaluate Atumelnant in Adults With Congenital Adrenal HyperplasiaPhase 3RecruitingDec 11, 20252027-05 (estimated)
NCT07087054Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine RegimenPhase 3RecruitingNov 19, 20252027-08 (estimated)
NCT05907291Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn)Phase 2CompletedJul 3, 2023Aug 22, 2025 (actual)
NCT05804669A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's SyndromePhase 1/Phase 2Active, not recruitingOct 12, 20232026-10 (estimated)
NCT07570082Drug-Drug Interaction Study of Atumelnant in Healthy ParticipantsPhase 1CompletedMay 28, 2026Jun 30, 2026 (actual)
NCT07129252A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid TumorsPhase 1/Phase 2RecruitingNov 26, 20252027-08 (estimated)
NCT04261712A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)Phase 2TerminatedJan 29, 2020Jun 30, 2026 (actual)
NCT05192382A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-2)Phase 3TerminatedDec 17, 2021Jan 20, 2024 (actual)
NCT04837040A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of AcromegalyPhase 3TerminatedMay 12, 2021Jul 10, 2023 (actual)
NCT06712823An Extension Study to Evaluate Safety and Efficacy of Atumelnant in Participants With Congenital Adrenal HyperplasiaPhase 2RecruitingFeb 25, 20252029-07 (estimated)
NCT05361668Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid SyndromePhase 2CompletedApr 22, 2022Mar 7, 2024 (actual)
NCT07221084A Study to Assess Pharmacokinetics, Safety, and Tolerability of Atumelnant in Healthy Japanese and Caucasian ParticipantsPhase 1CompletedOct 28, 2025Feb 7, 2026 (actual)
NCT03792555A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Evolve)Phase 2CompletedMar 11, 2019Jul 15, 2020 (actual)
NCT03789656An Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Edge)Phase 2CompletedMar 12, 2019Aug 3, 2020 (actual)
NCT06048887Single and Multiple-Ascending Dose Study of CRN04894 in Healthy VolunteersPhase 1CompletedDec 18, 2020Apr 11, 2022 (actual)
NCT03936166A Single and Multiple-Ascending Dose Study of CRN01941 in Healthy Adult VolunteersPhase 1CompletedApr 29, 2019Dec 16, 2019 (actual)
NCT04246749Mass Balance and Pharmacokinetics of [14C]-CRN00808 in Healthy VolunteersPhase 1CompletedSep 17, 2019Oct 25, 2019 (actual)
NCT03276858Single and Multiple-Ascending Dose Study of CRN00808 in Healthy VolunteersPhase 1CompletedSep 22, 2017Apr 30, 2018 (actual)

FDA records (last 2 years)

NIH awards 15

Annual award amounts. Total $10.3M.

Raises and investors new

Form D raises come from the company’s own SEC filing (last 2 years).

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LinkedIn page linked from the company's own site: source · seen 2026-10-12

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