COMPANY
Aridis Pharmaceuticals
Aridis’ proprietary mAb discovery platforms, ⅄PEX and MabIgX®, recover and immortalize the antibody-producing cells (called ‘B-cells’) from these individuals, turning them into therapeutic antibody producing factories. From company website Source · Oct 13, 2026
Timeline
- Trial start Phase 3: A Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin in Mechanically Ventilated Adult Subjects - 2 source ↗
- Trial start Phase 3: Adjunctive Therapy to Antibiotics in the Treatment of S. Aureus Ventilator-Associated Pneumonia With AR-301 source ↗
- Trial start Phase 1/Phase 2: SAD and MAD of Inhaled AR-501 in Health Adults and P. Aeruginosa Infected Cystic Fibrosis Subjects source ↗
- Trial start Phase 2: Adjunctive Therapeutic Treatment With Human Monoclonal Antibody AR-105 (Aerucin®) in P. Aeruginosa Pneumonia source ↗
- Trial start Phase 1: Study of Single Doses of IV Aerucin in Healthy Adults source ↗
- Trial start Phase 1/Phase 2: Safety, Pharmacokinetics and Efficacy of KBSA301 in Severe Pneumonia (S. Aureus) source ↗
Clinical trials (lead sponsor) 6
| Record | Title | Phase | Status | Start | Primary completion |
|---|---|---|---|---|---|
| NCT05331885 | A Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin in Mechanically Ventilated Adult Subjects - 2 | Phase 3 | Terminated | Sep 2, 2022 | Jul 8, 2024 (actual) |
| NCT03816956 | Adjunctive Therapy to Antibiotics in the Treatment of S. Aureus Ventilator-Associated Pneumonia With AR-301 | Phase 3 | Completed | May 3, 2019 | Oct 28, 2022 (actual) |
| NCT03669614 | SAD and MAD of Inhaled AR-501 in Health Adults and P. Aeruginosa Infected Cystic Fibrosis Subjects | Phase 1/Phase 2 | Unknown status (ClinicalTrials.gov) | Dec 7, 2018 | 2023-07 (estimated) |
| NCT03027609 | Adjunctive Therapeutic Treatment With Human Monoclonal Antibody AR-105 (Aerucin®) in P. Aeruginosa Pneumonia | Phase 2 | Completed | Mar 29, 2017 | Apr 25, 2019 (actual) |
| NCT01589185 | Safety, Pharmacokinetics and Efficacy of KBSA301 in Severe Pneumonia (S. Aureus) | Phase 1/Phase 2 | Completed | 2012-05 | 2016-05 (actual) |
| NCT02486770 | Study of Single Doses of IV Aerucin in Healthy Adults | Phase 1 | Completed | 2015-04 | 2015-09 (actual) |
NIH awards 18
- NIH contract (government contract; not a grant and not an investment round) 272201300016C-6-0-1 FY2016: $127,822 awarded for that fiscal year; activity N01 (OTHER_NIH); PI TRUONG, VU; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Developmen source ↗
- NIH contract (government contract; not a grant and not an investment round) 272201300016C-6-0-2 FY2016: $127,822 awarded for that fiscal year; activity N01 (OTHER_NIH); PI TRUONG, VU; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Developmen source ↗
- NIH contract (government contract; not a grant and not an investment round) 272201300016C-6-0-3 FY2016: $127,822 awarded for that fiscal year; activity N01 (OTHER_NIH); PI TRUONG, VU; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Developmen source ↗
- NIH award 5R43AI108083-02 FY2015: $282,803 awarded for that fiscal year; activity R43 (SBIR); PI TRUONG, VU L.; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Stable Vaccines Delivered on Oral Thin source ↗
- NIH contract (government contract; not a grant and not an investment round) 272201300016C-1-0-1 FY2015: $700,798 awarded for that fiscal year; activity N01 (OTHER_NIH); PI TRUONG, VU; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Developmen source ↗
- NIH contract (government contract; not a grant and not an investment round) 272201300016C-1-0-2 FY2015: $620,545 awarded for that fiscal year; activity N01 (OTHER_NIH); PI TRUONG, VU; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Developmen source ↗
- NIH contract (government contract; not a grant and not an investment round) 272201300016C-1-0-3 FY2015: $620,545 awarded for that fiscal year; activity N01 (OTHER_NIH); PI TRUONG, VU; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Developmen source ↗
- NIH award 1R43AI108083-01A1 FY2014: $283,500 awarded for that fiscal year; activity R43 (SBIR); PI TRUONG, VU L.; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Stable Vaccines Delivered on Oral Th source ↗
- NIH award 5R42AI072866-05 FY2013: $999,998 awarded for that fiscal year; activity R42 (STTR); PI PATZER, ERIC JOHN; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Human Monoclonal Antibody To Treat source ↗
- NIH contract (government contract; not a grant and not an investment round) 272201300016C-0-0-1 FY2013: $4,784,675 awarded for that fiscal year; activity N01 (OTHER_NIH); PI TRUONG, VU; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Developm source ↗
- NIH award 5R42AI072866-04 FY2012: $999,998 awarded for that fiscal year; activity R42 (STTR); PI PATZER, ERIC JOHN; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Human Monoclonal Antibody To Treat source ↗
- NIH award 2R42AI072866-03 FY2011: $922,387 awarded for that fiscal year; activity R42 (STTR); PI PATZER, ERIC JOHN; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Human Monoclonal Antibody To Treat source ↗
- NIH award 5R43AI081400-02 FY2010: $299,869 awarded for that fiscal year; activity R43 (SBIR); PI TRUONG, VU L.; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Inhalable Gallium Nitrate Anti-Infecti source ↗
- NIH award 1R43AI081400-01A1 FY2009: $299,960 awarded for that fiscal year; activity R43 (SBIR); PI TRUONG, VU L.; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Inhalable Gallium Nitrate Anti-Infec source ↗
- NIH award 5R41AI072866-02 FY2008: $243,632 awarded for that fiscal year; activity R41 (STTR); PI PATZER, ERIC JOHN; recipient as written: ARIDIS PHARMACEUTICALS, LLC, Los Gatos, CA. Human Monoclonal Antibody To Treat source ↗
- NIH award 1R41AI072866-01A1 FY2007: $299,997 awarded for that fiscal year; activity R41 (STTR); PI PATZER, ERIC JOHN; recipient as written: ARIDIS PHARMACEUTICALS, LLC, SAN JOSE, CA. Human Monoclonal Antibody To Trea source ↗
- NIH award 5R43AI063829-02 FY2006: $501,698 awarded for that fiscal year; activity R43 (SBIR); PI PATZER, ERIC JOHN; recipient as written: ARIDIS PHARMACEUTICALS, LLC, SAN JOSE, CA. Live, oral, heat Stable S. typhi TY source ↗
- NIH award 1R43AI063829-01A1 FY2005: $472,908 awarded for that fiscal year; activity R43 (SBIR); PI PATZER, ERIC JOHN; recipient as written: ARIDIS PHARMACEUTICALS, LLC, SAN JOSE, CA. Live, oral, heat Stable S. typhi source ↗