COMPANY

NeuroWave Systems

HQ: Beachwood, OH source · neurowavesystems.com ↗ · Midwest

FDA-cleared device company Past trials only

Keywords: medical device medical devices neurology Depth of Anesthesia Anesthesia

Location: Beachwood, OH · source · Oct 15, 2026

Profile checked Oct 10, 2026

2Trials (company is sponsor)15NIH grants

Timeline

Mar 13, 2018 Trial start Phase 1: The Effect of Low Dose Intra-operative Ketamine on Closed-loop Controlled General Anesthesia source ↗
2014-06 Trial start —: Effectiveness of the NeuroSENSE for Monitoring the Hypnotic Depth of Anesthesia source ↗

Clinical trials (lead sponsor) 2

Record	Title	Phase	Status	Start	Primary completion
NCT02088671	Effectiveness of the NeuroSENSE for Monitoring the Hypnotic Depth of Anesthesia	Not listed	Completed	2014-06	2014-12 (actual)
NCT03009409	The Effect of Low Dose Intra-operative Ketamine on Closed-loop Controlled General Anesthesia	Phase 1	Completed	Mar 13, 2018	Oct 17, 2018 (actual)

NIH awards 15

Annual award amounts. Total $7.0M.

Aug 27, 2020 NIH award 5R44GM112358-03 FY2020: $832,521 awarded for that fiscal year; activity R44 (SBIR); PI BIBIAN, STEPHANE; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. Automated Intravenous Anesthesia Delive source ↗
Sep 16, 2019 NIH award 2R44GM112358-02 FY2019: $663,684 awarded for that fiscal year; activity R44 (SBIR); PI BIBIAN, STEPHANE; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. Automated Intravenous Anesthesia Delive source ↗
Jun 10, 2019 NIH award 1R43DA049620-01 FY2019: $244,569 awarded for that fiscal year; activity R43 (SBIR); PI ZIKOV, TATJANA; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. NeoGUARD: An easy-to-use, low-cost brain source ↗
Sep 8, 2014 NIH award 1R43GM112358-01 FY2014: $217,487 awarded for that fiscal year; activity R43 (SBIR); PI BIBIAN, STEPHANE; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. Automated Intravenous Anesthesia Delive source ↗
Sep 16, 2013 NIH award 1R43GM108264-01 FY2013: $357,616 awarded for that fiscal year; activity R43 (SBIR); PI ZIKOV, TATJANA; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. New Quantitative Monitor for Continuous A source ↗
Jul 14, 2011 NIH award 5R43MH086985-02 FY2011: $249,923 awarded for that fiscal year; activity R43 (SBIR); PI BIBIAN, STEPHANE; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. NeuroBehavioral Tool for Assessment of source ↗
Aug 18, 2010 NIH award 5R44HL078442-03 FY2010: $642,779 awarded for that fiscal year; activity R44 (SBIR); PI BIBIAN, STEPHANE; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. Novel Algorithms and Device for Quantif source ↗
Jun 25, 2010 NIH award 1R43MH086985-01A1 FY2010: $249,847 awarded for that fiscal year; activity R43 (SBIR); PI BIBIAN, STEPHANE; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. NeuroBehavioral Tool for Assessment o source ↗
Jun 18, 2010 NIH award 5U44NS057969-06 FY2010: $744,488 awarded for that fiscal year; activity U44 (SBIR); PI BIBIAN, STEPHANE; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. Field Deployable, Automatic, EEG Seizur source ↗
Aug 26, 2009 NIH award 2R44HL078442-02 FY2009: $604,356 awarded for that fiscal year; activity R44 (SBIR); PI MODARRES, MO; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. Novel Algorithms and Device for Quantificat source ↗
Jun 25, 2009 NIH award 5U44NS057969-05 FY2009: $748,584 awarded for that fiscal year; activity U44 (SBIR); PI MODARRES, MO; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. Field Deployable, Automatic, EEG Seizure De source ↗
Sep 9, 2008 NIH award 6R44MH067464-04 FY2008: $382,195 awarded for that fiscal year; activity R44 (SBIR); PI MODARRES, MO; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. Wireless EEG and Attention Evaluation Syste source ↗
Aug 29, 2008 NIH award 6U44NS057969-04 FY2008: $388,430 awarded for that fiscal year; activity U44 (SBIR); PI MODARRES, MO; recipient as written: NEUROWAVE SYSTEMS, INC., Beachwood, OH. Field Deployable, Automatic, EEG Seizure De source ↗
Aug 29, 2008 NIH award 6R44NS046978-04 FY2006: $411,427 awarded for that fiscal year; activity R44 (SBIR); PI ZIKOV, TATJANA NONE; recipient as written: NEUROWAVE SYSTEMS, INC., CLEVELAND HEIGHTS, OH. Wireless EEG/PSG System with source ↗
Aug 29, 2008 NIH award 6R44NS047815-04 FY2007: $282,259 awarded for that fiscal year; activity R44 (SBIR); PI ZIKOV, TATJANA NONE; recipient as written: NEUROWAVE SYSTEMS, INC., CLEVELAND HEIGHTS, OH. Intraoperative Brain Dysfunc source ↗