COMPANY
aTyr Pharma
aTyr Pharma is listed on ClinicalTrials.gov as the lead sponsor of 9 studies; the most recently updated is “Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis” (Phase 3, completed), in Pulmonary Sarcoidosis. From public records Source · Oct 12, 2026
Timeline
- Trial start Phase 2: Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD) source ↗
- Trial start Phase 3: Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis source ↗
- Trial start Phase 2: Study to Evaluate the Safety and Efficacy of ATYR1923 (Efzofitimod) In Participants With Severe Pneumonia Related to COVID-19 source ↗
- Trial start Phase 1/Phase 2: Study of Intravenous ATYR1923 (Efzofitimod) for Pulmonary Sarcoidosis source ↗
- Trial start Phase 1/Phase 2: Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940 in Participants With Limb Girdle and Facioscapulohumeral Muscular Dystrophy (FSHD) source ↗
- Trial start Phase 1/Phase 2: Evaluate Safety and Biological Activity of ATYR1940 in Participants With Early Onset Facioscapulohumeral Muscular Dystrophy source ↗
- Trial start Phase 1/Phase 2: Evaluate Safety and Biological Activity of ATYR1940 in Participants With Limb Girdle Muscular Dystrophy 2B (LGMD2B) and Facioscapulohumeral Muscular Dystrophy (FSHD) source ↗
- Trial start Phase 1/Phase 2: Safety, Tolerability, Pharmacokinetics (PK), and Activity of ATYR1940 in Participants With Muscular Dystrophy - Study Extension source ↗
- Trial start Phase 1/Phase 2: Safety, Tolerability, Pharmacokinetics, and Biological Activity of ATYR1940 in Adult Participants With Muscular Dystrophy source ↗
Clinical trials (lead sponsor) 9
| Record | Title | Phase | Status | Start | Primary completion |
|---|---|---|---|---|---|
| NCT05415137 | Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis | Phase 3 | Completed | Sep 15, 2022 | Jun 25, 2025 (actual) |
| NCT05892614 | Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD) | Phase 2 | Recruiting | Oct 26, 2023 | 2026-04 (estimated) |
| NCT02836418 | Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940 in Participants With Limb Girdle and Facioscapulohumeral Muscular Dystrophy (FSHD) | Phase 1/Phase 2 | Completed | Jul 13, 2016 | Apr 18, 2017 (actual) |
| NCT02579239 | Evaluate Safety and Biological Activity of ATYR1940 in Participants With Limb Girdle Muscular Dystrophy 2B (LGMD2B) and Facioscapulohumeral Muscular Dystrophy (FSHD) | Phase 1/Phase 2 | Completed | Nov 30, 2015 | Oct 5, 2016 (actual) |
| NCT02603562 | Evaluate Safety and Biological Activity of ATYR1940 in Participants With Early Onset Facioscapulohumeral Muscular Dystrophy | Phase 1/Phase 2 | Completed | Mar 30, 2016 | Dec 12, 2016 (actual) |
| NCT02531217 | Safety, Tolerability, Pharmacokinetics (PK), and Activity of ATYR1940 in Participants With Muscular Dystrophy - Study Extension | Phase 1/Phase 2 | Completed | Aug 13, 2015 | May 26, 2016 (actual) |
| NCT04412668 | Study to Evaluate the Safety and Efficacy of ATYR1923 (Efzofitimod) In Participants With Severe Pneumonia Related to COVID-19 | Phase 2 | Completed | Jun 4, 2020 | Oct 23, 2020 (actual) |
| NCT03824392 | Study of Intravenous ATYR1923 (Efzofitimod) for Pulmonary Sarcoidosis | Phase 1/Phase 2 | Completed | Jan 29, 2019 | Jun 29, 2021 (actual) |
| NCT02239224 | Safety, Tolerability, Pharmacokinetics, and Biological Activity of ATYR1940 in Adult Participants With Muscular Dystrophy | Phase 1/Phase 2 | Completed | Sep 4, 2014 | Dec 14, 2015 (actual) |
Raises and investors new
- InvestorListed in the portfolio of Sofinnova Investments (captured Oct 12, 2026). portfolio page ↗