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COMPANY

Immune-Onc Therapeutics, Inc.

HQ: Palo Alto, CA source · immune-onc.com ↗ · West Coast

Clinical Phase 1

Keywords: oncology cancer acute myeloid leukemia AML With Monocytic Differentiation CMML IO-202 IO-108

Location: Palo Alto, CA · source · Oct 14, 2026

Profile checked Oct 10, 2026

4Trials (company is sponsor)2NIH grants

Timeline

  1. Trial start 1: Dose Confirmation and Dose Expansion Phase 1 Study of IO-108 and IO-108 + Anti-PD-1 in Solid Tumors source ↗
  2. Trial start Phase 1: Dose-Escalation and Dose-Expansion Study of IO-202 and IO-202+Pembrolizumab in Solid Tumors source ↗
  3. Trial start Phase 1: First-in-human Study of IO-108 as Single Agent and in Combination With a PD-1 Immune Check Point Inhibitor in Patients With Advanced Solid Tumors source ↗
  4. Trial start Phase 1: IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML source ↗

Clinical trials (lead sponsor) 4

RecordTitlePhaseStatusStartPrimary completion
NCT04372433IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMMLPhase 1CompletedSep 14, 2020Jan 31, 2025 (actual)
NCT05309187Dose-Escalation and Dose-Expansion Study of IO-202 and IO-202+Pembrolizumab in Solid TumorsPhase 1CompletedApr 11, 2022Mar 29, 2024 (actual)
NCT05054348First-in-human Study of IO-108 as Single Agent and in Combination With a PD-1 Immune Check Point Inhibitor in Patients With Advanced Solid TumorsPhase 1CompletedSep 30, 2021Apr 29, 2024 (actual)
NCT05508100Dose Confirmation and Dose Expansion Phase 1 Study of IO-108 and IO-108 + Anti-PD-1 in Solid Tumors1CompletedSep 9, 2022Apr 30, 2024 (actual)

NIH awards 2

Annual award amounts. Total $2.1M.

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