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COMPANY

Edwards Lifesciences

HQ: Irvine, CA source · edwards.com ↗

FDA-cleared device company Past trials only

420 open jobs · last seen Oct 23, 2026 · 67 sources

Location: Irvine, CA · source · Oct 14, 2026

Profile checked Oct 10, 2026

Keywords: Aortic Valve Stenosis Tricuspid Regurgitation Mitral Regurgitation Mitral Valve Insufficiency Heart Valve Diseases Heart Diseases Cardiovascular Diseases Tricuspid Valve Insufficiency Heart Failure Pulmonary Valve Insufficiency Complex Congenital Heart Defect Congenital Heart Disease Tricuspid Valve Disease Tricuspid Valve Regurgitation Mitral Stenosis Aortic Stenosis Aortic Valve Insufficiency Tetralogy of Fallot Pulmonary Regurgitation Aortic Valve Replacement Aortic Valve Disease Severe Aortic Stenosis Mitral Valve Regurgitation (Degenerative or Functional) Mitral Insufficiency Dysfunctional RVOT Conduit Pulmonary Valve Degeneration Mitral Valve Regurgitation Mitral Valve Disease Tricuspid Insufficiency RVOT Anomaly Mitral Disease Atrial Appendage Degenerative Mitral Valve Disease Functional Mitral Regurgitation Cardiopulmonary Bypass Surgery Mitral Valve Replacement Calcific Aortic Stenosis Pulmonary Valve Stenosis Congenital Heart Defects

420+1 patient-care hiddenOpen jobs128Trials (company is sponsor)17FDA records (2 yrs)

Hiring

TitleLocation (from posting)Employer postedFirst seen
Chemist ISpain - Moncada - ValenciaOct 23, 2026Oct 23, 2026
Sales Rep, TMTT, TokyoJapan-TokyoOct 23, 2026Oct 23, 2026
Senior Territory Manager, THVAustralia-Queensland-RemoteOct 22, 2026Oct 12, 2026
Director, Regulatory Counsel6 locations, including California Irvine, USAOct 22, 2026Oct 12, 2026
Patent ProsecutorUSA - California – IrvineOct 22, 2026Oct 12, 2026

See all 420 jobs

Trial and FDA signals

Job counts as of Oct 18, 2026. All trial and FDA signals

Timeline

  1. Trial start —: INSPIRIS RESILIA Aortic Valve, Valve-in-Valve Surveillance Study source ↗
  2. Trial start Not phased (device or behavioral study): ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral source ↗
  3. Trial start —: The CLASP III TR CED Study source ↗
  4. Trial start Not phased (device or behavioral study): Early Feasibility Study of the Edwards APTURE Transcatheter Shunt System source ↗
  5. Trial start —: CLAARITY is a Prospective, Observational, Single-arm, Multi-center, Post-market US Study Designed to Evaluate the Safety and Performance of the ECLIPTIS Left Atrial Appendage Exclusion System for E source ↗
  6. Trial start —: TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study) source ↗
  7. Trial start Not phased (device or behavioral study): Autus Valve Continued Access Study (CAS) source ↗
  8. FDA FDA 510(k) clearance: ECLIPTIS Left Atrial Appendage Exclusion System (ECS135); ECLIPTIS Left Atrial Appendage Exclusion System (ECS140); ECLIPTIS Left Atrial Appendage Exclusion System (ECS145); ECLI source ↗
  9. Trial start —: KONECT RESILIA Aortic Valved Conduit (AVC) Real-world Study Assessing Safety and Performance source ↗
  10. FDA FDA 510(k) clearance: Respiration Rate algorithm — K251326, Jun 11, 2026. Applicant at approval: Edwards Lifesciences, LLC. source ↗
  11. FDA FDA 510(k) clearance: Fogarty Spring Clips, Handleless Clamps, and Clamp Inserts — K260105, Jun 5, 2026. Applicant at approval: Edwards Lifesciences. source ↗
  12. FDA FDA 510(k) clearance: Edwards eSheath+ introducer set — K254279, Apr 17, 2026. Applicant at approval: Edwards Lifesciences. source ↗
  13. FDA FDA 510(k) clearance: HemoSphere Nano Monitor (HSNANO1) — K253186, Feb 24, 2026. Applicant at approval: Edwards Lifesciences, LLC. source ↗
  14. FDA FDA PMA approval: SAPIEN M3 Transcatheter Mitral Valve Replacement System — P250019, Dec 22, 2025. Applicant at approval: Edwards Lifesciences, LLC. source ↗
  15. FDA FDA 510(k) clearance: HemoSphere Alta Advanced Monitoring Platform (ALTAALL1; ALTACR1; ALTASR1) — K252533, Dec 18, 2025. Applicant at approval: Edwards Lifesciences. source ↗
  16. FDA FDA 510(k) clearance: HemoSphere Stream Module — K253034, Oct 21, 2025. Applicant at approval: Edwards Lifesciences. source ↗
  17. FDA FDA 510(k) clearance: Edwards MC3 Tricuspid annuloplasty ring (4900) — K251982, Sep 23, 2025. Applicant at approval: Edwards Lifesciences, LLC. source ↗
  18. FDA FDA 510(k) clearance: Carpentier-Edwards Physio Annuloplasty Ring (4450) — K251688, Sep 17, 2025. Applicant at approval: Edwards Lifesciences, LLC. source ↗
  19. FDA FDA 510(k) clearance: Edwards eSheath Optima introducer set — K252364, Aug 29, 2025. Applicant at approval: Edwards Lifesciences. source ↗
  20. Trial start —: Real World Data Collection on the INSPIRIS RESILIA Aortic Valve source ↗
  21. FDA FDA 510(k) clearance: HemoSphere Advanced Monitor (HEM1); HemoSphere Technology Module (HEMTOM10); HemoSphere ClearSight Module (HEMCSM10); Smart Pressure Controller (PC1Q); Acumen IQ Plus Finger Cuff source ↗
  22. Trial start —: MITRIS China Post Market Clinical Follow-up (PMCF) Study source ↗
  23. FDA FDA 510(k) clearance: Hypertension Prediction Index (HePI) Algorithm — K242518, May 15, 2025. Applicant at approval: Edwards Lifesciences, LLC. source ↗
  24. FDA FDA 510(k) clearance: Edwards eSheath Optima introducer set — K244046, Mar 27, 2025. Applicant at approval: Edwards Lifesciences. source ↗
  25. FDA FDA 510(k) clearance: FloTrac sensors; FloTrac Jr sensors; Acumen IQ sensors; VolumeView sensors — K242909, Mar 21, 2025. Applicant at approval: Edwards Lifesciences, LLC. source ↗

Showing 25 of 67 dated events.

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) Showing 50 of 128

RecordTitlePhaseStatusStartPrimary completion
NCT05172973ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic ValvesNot phased (device or behavioral study)RecruitingNov 22, 20232029-03 (estimated)
NCT03779490Transcatheter Repair of Tricuspid Regurgitation With Edwards Cardioband TR System Post Market Study (TriBAND)Not listedActive, not recruitingJul 24, 2019Sep 30, 2022 (actual)
NCT04153292The ENCIRCLE TrialNot phased (device or behavioral study)Active, not recruitingNov 12, 2020Oct 10, 2027 (estimated)
NCT07859709The CLASP III TR CED StudyNot listedNot yet recruitingOct 15, 2026Dec 31, 2030 (estimated)
NCT07858799Early Feasibility Study of the Edwards APTURE Transcatheter Shunt SystemNot phased (device or behavioral study)Recruiting2026-102027-02 (estimated)
NCT05378386ALTERRA Post-Approval StudyNot listedActive, not recruitingMay 12, 2022Sep 25, 2025 (actual)
NCT03523416Early Feasibility Study - Edwards APTURE Transcatheter Shunt SystemNot phased (device or behavioral study)RecruitingJul 31, 20182027-04 (estimated)
NCT05404880INSPIRIS China PMCF StudyNot listedActive, not recruitingJul 13, 20222034-03 (estimated)
NCT07619872KONECT RESILIA Aortic Valved Conduit (AVC) Real-world Study Assessing Safety and PerformanceNot listedRecruitingJun 25, 2026Dec 31, 2028 (estimated)
NCT07120048Real World Data Collection on the INSPIRIS RESILIA Aortic ValveNot listedRecruitingJul 30, 20252026-12 (estimated)
NCT06833476TTVR STRONG Under Coverage With Evidence Development (CED) StudyNot listedRecruitingMar 19, 2025Dec 30, 2027 (estimated)
NCT05006404Autus Valve Pivotal StudyNot phased (device or behavioral study)Active, not recruitingFeb 5, 2024Aug 24, 2026 (actual)
NCT03230747SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral RegurgitationNot phased (device or behavioral study)CompletedSep 14, 2017Jun 16, 2021 (actual)
NCT05172960ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart ValveNot phased (device or behavioral study)RecruitingJun 20, 20222027-07 (estimated)
NCT04919980TVMR With the INNOVALVE System Trial - Early Feasibility StudyNot phased (device or behavioral study)RecruitingSep 1, 2022Jul 1, 2028 (estimated)
NCT04097145Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical TrialNot phased (device or behavioral study)RecruitingDec 11, 2019Dec 31, 2027 (estimated)
NCT06569602Real World European Investigation of Safety and Clinical Efficacy of the EVOQUE System (TRISCEND III EU)Not listedRecruitingOct 1, 2024Sep 30, 2030 (estimated)
NCT04375332Beating Heart Mitral Valve Repair With the HARPOON™ SystemNot phased (device or behavioral study)Active, not recruitingDec 16, 2020Dec 20, 2027 (estimated)
NCT04430075MiCLASP Post Market Clinical Follow-Up (PMCF) StudyNot listedActive, not recruitingAug 23, 2019Sep 4, 2025 (actual)
NCT05168826China S3 PMS: SAPIEN 3 China Post Market Registry StudyNot listedActive, not recruitingJan 24, 20222035-12 (estimated)
NCT07466745Autus Valve Continued Access Study (CAS)Not phased (device or behavioral study)RecruitingJul 27, 2026Oct 30, 2027 (estimated)
NCT04902053INSPIRIS RESILIA Aortic Valve, Valve-in-Valve Surveillance StudyNot listedSuspended2028-062030-12 (estimated)
NCT07742839CLAARITY is a Prospective, Observational, Single-arm, Multi-center, Post-market US Study Designed to Evaluate the Safety and Performance of the ECLIPTIS Left Atrial Appendage Exclusion System for Exclusion of the Left Atrial Appendage (LAA) During Concomitant Open-heart Cardiac Surgery.Not listedNot yet recruitingSep 30, 2026Jul 10, 2027 (estimated)
NCT02744677COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionNot phased (device or behavioral study)RecruitingJul 5, 20162026-12 (estimated)
NCT04614402Transcatheter Repair of Tricuspid Regurgitation With Edwards PASCAL Transcatheter Valve Repair SystemNot listedActive, not recruitingJan 15, 2021Apr 20, 2023 (actual)
NCT03745313Edwards CLASP TR EFSNot phased (device or behavioral study)CompletedFeb 5, 2019May 11, 2021 (actual)
NCT03706833Edwards PASCAL CLASP IID/IIF Pivotal Clinical TrialNot phased (device or behavioral study)Active, not recruitingNov 30, 2018Jun 30, 2026 (estimated)
NCT07684313TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study)Not listedNot yet recruiting2026-082030-08 (estimated)
NCT05083403HPI (Hypotension Prediction Index) Care TrialNot phased (device or behavioral study)TerminatedMar 28, 2022May 14, 2024 (actual)
NCT05686317ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt SystemNot phased (device or behavioral study)Active, not recruitingApr 1, 2023Nov 1, 2026 (estimated)
NCT05526560Real-world Clinical Outcomes of the MITRIS RESILIA Mitral ValveNot listedActive, not recruitingJan 11, 20232028-01 (estimated)
NCT03382457Clinical Study of Edwards Cardioband FIT Valve Repair SystemNot phased (device or behavioral study)Active, not recruitingJul 1, 2018Dec 31, 2026 (estimated)
NCT042214902019-06 TRISCEND StudyNot phased (device or behavioral study)Active, not recruitingMay 6, 2020Jan 5, 2024 (actual)
NCT01757665ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE)Not phased (device or behavioral study)CompletedDec 11, 20122017-08 (actual)
NCT04555967SAPIEN 3 Ultra System PMCFNot listedActive, not recruitingJun 30, 2020Sep 24, 2021 (actual)
NCT02718001Edwards EVOQUE Eos MISCEND StudyNot phased (device or behavioral study)Active, not recruitingFeb 6, 2015Apr 30, 2028 (estimated)
NCT04482062TRISCEND II Pivotal TrialNot phased (device or behavioral study)Active, not recruitingApr 9, 2021Dec 5, 2025 (actual)
NCT03170349The CLASP Study Edwards PASCAL TrAnScatheter Mitral Valve RePair System StudyNot phased (device or behavioral study)CompletedJun 27, 2017Jul 30, 2020 (actual)
NCT04860765COMPASSION S3 Post-Approval StudyNot listedActive, not recruitingApr 13, 20212030-08 (estimated)
NCT04000607Exploratory Study of the Edwards APTURE Transcatheter Shunt System (ALT-FLOW Canada)Not phased (device or behavioral study)Active, not recruitingJul 10, 2019Nov 3, 2023 (actual)
NCT02675114PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic StenosisNot phased (device or behavioral study)Active, not recruiting2016-03Nov 16, 2020 (actual)
NCT07059793MITRIS China Post Market Clinical Follow-up (PMCF) StudyNot listedRecruitingJul 8, 20252028-12 (estimated)
NCT06167213ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - MitralNot phased (device or behavioral study)Not yet recruiting2027-012029-03 (estimated)
NCT04889872PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVRNot phased (device or behavioral study)RecruitingOct 12, 20212029-06 (estimated)
NCT02987387COMPASSION XT PAS - Post-approval Study of the SAPIEN XT THV in Patients With Pulmonary Valve DysfunctionNot listedCompletedJul 17, 2017Aug 9, 2021 (actual)
NCT03517436ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic StenosisNot phased (device or behavioral study)Active, not recruitingSep 18, 2018Oct 2, 2020 (actual)
NCT03193801PARTNER 3 Trial - Mitral Valve in ValveNot phased (device or behavioral study)Active, not recruitingFeb 1, 2018Aug 16, 2022 (actual)
NCT03130777ALTERRA: SAPIEN 3 THV With the Alterra Adaptive PrestentNot phased (device or behavioral study)Active, not recruitingAug 22, 2017Jul 14, 2022 (actual)
NCT03466918China S3: Safety and Effectiveness of Edwards Lifesciences SAPIEN 3 THV in the Chinese PopulationNot phased (device or behavioral study)CompletedMay 23, 2018Jul 3, 2019 (actual)
NCT04860752SAPIEN 3 Ultra EU PMSNot listedCompletedApr 20, 2021Jul 22, 2024 (actual)

FDA records (last 2 years)

Open jobs 420

1 patient-care job hidden (phlebotomy, plasma-center, nursing and similar care roles; 421 open jobs in total).

TitleLocation (from posting, not HQ)Employer postedFirst seenLevel
Chemist ISpain - Moncada - ValenciaOct 23, 2026Oct 23, 2026Not stated
Sales Rep, TMTT, TokyoJapan-TokyoOct 23, 2026Oct 23, 2026Not stated
Senior Territory Manager, THVAustralia-Queensland-RemoteOct 22, 2026Oct 12, 2026Not stated
Director, Regulatory Counsel6 locations, including California Irvine, USAOct 22, 2026Oct 12, 2026Senior
Patent ProsecutorUSA - California – IrvineOct 22, 2026Oct 12, 2026Mid
テリトリーマネージャー, THV, 東京Japan-Tokyo HQOct 22, 2026Oct 12, 2026Mid
Senior Engineer, NPD ManufacturingUSA - California – IrvineOct 22, 2026Oct 17, 2026Not stated
Associate Contracts AnalystIrvine, CAOct 22, 2026Oct 23, 2026Not stated
InspectorUSA - Utah – Salt Lake CityOct 22, 2026Oct 23, 2026Not stated
Senior Packager, PilotUSA - California – IrvineOct 22, 2026Oct 23, 2026Not stated
Senior Inspector, PilotUSA - California – IrvineOct 22, 2026Oct 23, 2026Not stated
Technician, Pilot QualityUSA - California – IrvineOct 22, 2026Oct 23, 2026Not stated
Area Sales Manager, Long Island, IHFMUSA - New York – Long IslandOct 22, 2026Oct 23, 2026Not stated
Senior Engineer, ManufacturingUSA - Utah – Salt Lake CityOct 22, 2026Oct 23, 2026Not stated
Director of Engineering, Advanced Catheters PEGUSA - Utah – Salt Lake CityOct 22, 2026Oct 23, 2026Not stated
Senior Supervisor, ManufacturingCosta Rica-Cartago-Wet PlantOct 22, 2026Oct 23, 2026Not stated
Senior BiostatisticianUSA - California – IrvineOct 22, 2026Oct 23, 2026Not stated
障碍者採用 Analyst, Sales Strategy and OperationsJapan-TokyoOct 22, 2026Oct 23, 2026Not stated
Sr AP Accountant, AccountingCzech Republic-PragueOct 22, 2026Oct 23, 2026Not stated
Sales Rep, TMTT, OsakaJapan-OsakaOct 22, 2026Oct 23, 2026Not stated
Senior Technician, MaintenanceUSA - California – IrvineOct 21, 2026Oct 12, 2026Senior
Associate Rep, Training SystemsUSA - California – IrvineOct 21, 2026Oct 12, 2026Entry
Sr Developer, ServiceNow HRSD2 locations (listed on the posting)Oct 21, 2026Oct 12, 2026Senior
Product Marketing Manager, SurgicalIndia-MumbaiOct 21, 2026Oct 12, 2026Mid
Manager, Business ContinuityCosta Rica-Cartago-BSCOct 21, 2026Oct 12, 2026Not stated
Field Clinical Specialist, Memphis, TMTTUSA - Tennessee - MemphisOct 21, 2026Oct 17, 2026Not stated
Second Shift Associate Inspector (Metals)USA - Utah – Salt Lake CityOct 21, 2026Oct 23, 2026Not stated
Principal Engineer, R&DUSA - California – IrvineOct 21, 2026Oct 23, 2026Not stated
Product SpecialistChina-Zhengzhou-FieldOct 21, 2026Oct 23, 2026Not stated
Engineer I , ManufacturingSingaporeOct 21, 2026Oct 23, 2026Not stated
Senior Director of Health Systems Partnerships (National Accounts) - THV12 locations, including Boston, Mass, USAOct 20, 2026Oct 12, 2026Senior
Senior Manager, Lifecycle ManagementUSA - California – IrvineOct 20, 2026Oct 12, 2026Not stated
テリトリーマネージャー, THV, 大阪Japan-OsakaOct 20, 2026Oct 12, 2026Mid
Senior Manufacturing Engineer, PilotUSA - California – IrvineOct 20, 2026Oct 14, 2026Not stated
Production Supply ClerkUSA - Utah – Salt Lake CityOct 20, 2026Oct 14, 2026Not stated
Territory Manager TMTT - East CanadaCanada-Montreal-FieldOct 20, 2026Oct 17, 2026Not stated
Senior Manager, Project ManagementUSA - California – IrvineOct 20, 2026Oct 20, 2026Not stated
Associate Heart Valve SpecialistSingaporeOct 20, 2026Oct 20, 2026Not stated
Principal BiostatisticianUSA - California – IrvineOct 20, 2026Oct 23, 2026Not stated
Senior MicrobiologistIrvine, CAOct 20, 2026Oct 23, 2026Not stated
THV Field Clinical Specialist(m/f/d) - Paris & Ile-de-France2 locations (listed on the posting)Oct 20, 2026Oct 23, 2026Not stated
Regional Director, Southern CA – Transcatheter Heart Valve2 locations, including California Irvine, USAOct 20, 2026Oct 23, 2026Not stated
Commercial Inventory AnalystUSA - California – IrvineOct 19, 2026Oct 12, 2026Not stated
Senior Manager, Program Management, SoftwareUSA - California – IrvineOct 19, 2026Oct 12, 2026Senior
Director, AI Clinical Operations & RegulatoryUSA - California – IrvineOct 19, 2026Oct 12, 2026Senior
Senior BiostatisticianIrvine, CAOct 19, 2026Oct 20, 2026Not stated
Principal Engineer, NPD-QualityUSA - California – IrvineOct 19, 2026Oct 20, 2026Not stated
Senior Analyst, Project ManagementUSA - Utah – Salt Lake CityOct 19, 2026Oct 20, 2026Not stated
Senior Engineer, PackagingUSA - California – IrvineOct 19, 2026Oct 20, 2026Not stated
Territory Manager, South Jersey- Transcatheter Heart ValveUSA - New Jersey – Cherry HillOct 19, 2026Oct 20, 2026Not stated

Level (Entry/Mid/Senior/Executive) is estimated from the job title and required years of experience. Descriptions are short excerpts (about the first 60 words) of the posting plus skills picked out of it; use Read full posting for the complete text.

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