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COMPANY

Metavention

HQ: Maple Grove, MN source · metavention.com ↗

Metavention is conducting clinical studies evaluating the safety and benefits of renal denervation using our iRF Denervation System in patients with high blood pressure. From company website Source · Oct 12, 2026

Keywords: Hypertension Metabolic Syndrome Type 2 Diabetes Mellitus Type 2 Diabetes Diabetes Endocrine, Nutritional and Metabolic Diseases (E00-E89) iRF System Hepatic Denervation iRF System Renal Denervation iRF System Multi-organ Denervation Metabolic Neuromodulation System

Location: Maple Grove, MN · source · Oct 15, 2026

Profile checked Oct 10, 2026

4Trials (company is sponsor)

Timeline

  1. Trial start Not phased (device or behavioral study): Multi-Organ Denervation With the iRF System to RedUce Sympathetic Drive source ↗
  2. Trial start Not phased (device or behavioral study): Evaluation of the Integrated Radio Frequency Denervation System for the Treatment of Hypertension source ↗
  3. Trial start Not phased (device or behavioral study): Evaluation of the Integrated Radio Frequency Denervation System to Improve Glycemic Control in Type 2 Diabetic Subjects source ↗
  4. Trial start Not phased (device or behavioral study): COMPLEMENT Study- A First in Human Study of Metabolic Neuromodulation Therapy source ↗

Clinical trials (lead sponsor) 4

RecordTitlePhaseStatusStartPrimary completion
NCT04285554Evaluation of the Integrated Radio Frequency Denervation System to Improve Glycemic Control in Type 2 Diabetic SubjectsNot phased (device or behavioral study)CompletedJul 28, 2020Mar 2, 2022 (actual)
NCT04740723Evaluation of the Integrated Radio Frequency Denervation System for the Treatment of HypertensionNot phased (device or behavioral study)CompletedFeb 6, 2021Oct 20, 2021 (actual)
NCT04917393Multi-Organ Denervation With the iRF System to RedUce Sympathetic DriveNot phased (device or behavioral study)Unknown status (ClinicalTrials.gov)Sep 13, 2021Oct 1, 2022 (estimated)
NCT02278068COMPLEMENT Study- A First in Human Study of Metabolic Neuromodulation TherapyNot phased (device or behavioral study)Completed2014-102019-05 (actual)
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