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COMPANY

Werewolf Therapeutics

HQ: Waltham, MA source · werewolftx.com ↗

Clinical Phase 2

Keywords: oncology immunology cancer protein engineering Non-Hodgkin Lymphoma WTX-330 WTX-124

Location: Waltham, MA · source · Oct 15, 2026

Profile checked Oct 10, 2026

3Trials (company is sponsor)

Timeline

  1. Trial start 1: A Phase 1b/2 Multisite Dose-finding and Expansion Study of WTX-330 in Adult Patients With Selected Advanced or Metastatic Solid Tumors or Lymphoma source ↗
  2. Trial start Phase 1: WTX-330 in Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphoma source ↗
  3. Trial start Phase 1: Dose Escalation and Expansion Study of WTX-124 as Monotherapy and in Combination With Pembrolizumab (Pembro) in Patients With Selected Advanced or Metastatic Solid Tumors source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 3

RecordTitlePhaseStatusStartPrimary completion
NCT05479812Dose Escalation and Expansion Study of WTX-124 as Monotherapy and in Combination With Pembrolizumab (Pembro) in Patients With Selected Advanced or Metastatic Solid TumorsPhase 1CompletedAug 15, 2022Apr 22, 2026 (actual)
NCT06939283A Phase 1b/2 Multisite Dose-finding and Expansion Study of WTX-330 in Adult Patients With Selected Advanced or Metastatic Solid Tumors or Lymphoma1Active, not recruitingMay 7, 20252028-08 (estimated)
NCT05678998WTX-330 in Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin LymphomaPhase 1CompletedDec 6, 2022Dec 23, 2024 (actual)
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