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COMPANY

Kiora Pharmaceuticals

HQ: Encinitas, CA source · kiorapharma.com ↗ · West Coast

Clinical Phase 2

Keywords: small molecule ophthalmology retinal disease Retinitis Pigmentosa Macular Edema Choroideremia Non-Syndromic Rod-Dominant Inherited Retinal Diseases Persistent Corneal Epithelial Defect Dry Eye Disease KIO-104 KIO-301 KIO-101

Location: Encinitas, CA · source · Oct 13, 2026

Profile checked Oct 10, 2026

$5.0MRaised (2 yrs)5Trials (company is sponsor)

Timeline

  1. Partnership Partnership / licensing: $1M (upfront, as published), announced Aug 19, 2026. Source: SEC filing. source ↗
  2. Raise Private placement: $5M (initial closing, as published); deal value up to $24M (not counted as received), announced Apr 7, 2026. Source: SEC filing. source ↗ · Form D filed Apr 21, 2026 SEC Form D ↗
  3. Trial start II: A Phase II Study of Intravitreal KIO-301 in Patients With Late-stage Retinitis Pigmentosa source ↗
  4. Trial start Phase 2: Safety, Tolerability and Efficacy of Intravitreal KIO-104 in Patients With Macular Edema source ↗
  5. Trial start 2: A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, Versus Vehicle Control in the Treatment of Dry Eye Disease in Patients With A source ↗
  6. Trial start I: A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS) source ↗
  7. Trial start Phase 2: A Study of the KIO-201 (Ocular Bandage Gel) for Improving Persistent Corneal Epithelial Defects source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Funding

Raised: $5.0M. Last 2 years.

Clinical trials (lead sponsor) 5

RecordTitlePhaseStatusStartPrimary completion
NCT06825702Safety, Tolerability and Efficacy of Intravitreal KIO-104 in Patients With Macular EdemaPhase 2RecruitingMay 1, 20252026-11 (estimated)
NCT06628947A Phase II Study of Intravitreal KIO-301 in Patients With Late-stage Retinitis PigmentosaIIRecruitingAug 29, 20252027-08 (estimated)
NCT05282953A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS)ICompletedNov 10, 2022Aug 10, 2023 (actual)
NCT05436288A Study of the KIO-201 (Ocular Bandage Gel) for Improving Persistent Corneal Epithelial DefectsPhase 2CompletedJul 1, 2022Dec 22, 2022 (actual)
NCT05629364A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, Versus Vehicle Control in the Treatment of Dry Eye Disease in Patients With Autoimmune Disease2TerminatedMar 15, 2023Jan 9, 2024 (actual)

Raises and investors new

Form D raises come from the company’s own SEC filing (last 2 years).

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